Cell surface display of functional human MHC class II proteins: yeast display versus insect cell display
نویسندگان
چکیده
منابع مشابه
Cell surface display of functional human MHC class II proteins: yeast display versus insect cell display.
Reliable and robust systems for engineering functional major histocompatibility complex class II (MHCII) proteins have proved elusive. Availability of such systems would enable the engineering of peptide-MHCII (pMHCII) complexes for therapeutic and diagnostic applications. In this paper, we have developed a system based on insect cell surface display that allows functional expression of heterod...
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in the past decade much effort has been devoted to the development of new expression systems and novel techniques for the surface display of heterologous proteins in yeast in order to improve their applications in biotechnology, food technology, pharmacology and medicine. heterologous protein-encoding genes are generally fused with genes coding for yeast cell wall proteins or their fragments re...
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ژورنال
عنوان ژورنال: Protein Engineering, Design and Selection
سال: 2011
ISSN: 1741-0134,1741-0126
DOI: 10.1093/protein/gzr035